Soram Idiyasan Chanu's Research work featured in 'The Hindu' and Molecular Neurobiology Journal
April 26 2016
Soram Idiyasan Chanu
Pix Courtesy - Neurobiology and Developmental Genetics Laboratory / University of Delhi (South Campus)
The name of the research scholar is Soram Idiyasan Chanu who is currently pursuing PhD in Delhi University, South Campus under Dr. Surajit Sarkar. The team led by Dr. Surajit Sarkar has been able to identify the target gene which can stop progression of Alzheimers, Parkinsons through Cancer drugs.
The original article was published in Molecular Neurobiology under Springer publications on Mar 21, 2016. The link is provided below:
http://link.springer.com/article/10.1007/s12035-016-9858-6.
Targeted Downregulation of dMyc Suppresses Pathogenesis of Human Neuronal Tauopathies in Drosophila by Limiting Heterochromatin Relaxation and Tau Hyperphosphorylation
Soram Idiyasan Chanu, Surajit Sarkar
Human tauopathies such as Alzheimer’s Disease (AD), frontotemporal dementia with parkinsonism linked to chromosome 17 (FTDP-17), Pick’s disease etc., are a group of neurodegenerative diseases which are characterized by abnormal hyperphosphorylation of tau that leads to formation of neurofibrillary tangles. Recapitulating several features of human neurodegenerative disorders, the Drosophila tauopathy model displays compromised lifespan, locomotor function impairment, and brain vacuolization in adult brain which is progressive and age dependent.
The link for the Hindu article is also provided below:
http://www.thehindu.com/sci-tech/health/cancer-drugs-can-stop-progression-of-alzheimers-parkinsons/article8513695.ece
Cancer drugs can stop progression of Alzheimer’s, Parkinson’s
In a breakthrough, researchers from the University of Delhi found that the progression of Alzheimer’s and Parkinson’s diseases can be suppressed or stopped by downregulating the expression level of d-myc in Drosophila (fruit fly). Since d-myc in an evolutionarily conserved human homolog of c-myc proto-oncogene, the findings in fruit fly may be applicable to humans as well.
Results of a study were published on March 21 in the journal Molecular Neurobiology.
* This information was provided by Oinam Premchand Singh who can be contacted at oinampremchand(At)gmail(DOT)com
This was posted on April 26 2016
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