TODAY -

E-Pao! Top Stories:: Manipuri Scientists part of Gene Discovery

Manipuri Scientists part of Gene Discovery
Information culled from NIH *



Gene Discovery Sheds Light on Causes of Rare Disease, Cancer
< Link Here , here , here , and here >

National Institute on Aging (NIA) researchers have discovered a new gene, FANCM, which sheds light on an important pathway involved in the repair of damaged DNA. Specifically, mutation in this gene is responsible for one of the forms of Fanconi anemia (FA), a rare genetic disorder that primarily affects children.

Like many rare, inherited diseases, understanding this gene’s role in the development of FA provides insights into other medical problems — in this case, age-related conditions including ovarian and pancreatic cancers, as well as leukemia, the researchers said.

Discovery of this gene and its protein provides a potential target for the development of drugs that can prevent or alleviate FA and a variety of cancers.

The finding is scheduled for advanced online publication in Nature Genetics (http://www.nature.com/ng/) during the week of August 21, 2005.
* AR Meetei et al, "A Human Orthologue of Archaeal DNA Repair Protein Hef is Defective in Fanconi Anemia Complementation Group M," Nature Genet., August 21, 2005, online.

"FA is a disease that appears to be the result of a breakdown in vital DNA repair mechanisms," said Weidong Wang, Ph.D., a senior investigator in the NIA’s Laboratory of Genetics, who led the study.

"Some scientists theorize that DNA damage, which gradually accumulates as we age, leads to malfunctioning genes and deteriorating tissues and organs as well as increased risk of cancer.

We believe that this new gene, FANCM, may be a potent cog in the DNA repair machinery," Wang said. "It is possible that we could learn how to promote the function of DNA repair complexes and thereby prevent the age-related accumulation of DNA damage."

....
...

The Manipuri Scientists who are part of a scientific group focussing on rare genetic disease, Fanconi anemia at Cincinnati Children Hospital medical centre are

a) Amom Ruhikanta Meetei did his BS and MS from Manipur University and completed his PhD from IISc , Bangalore.
He is an Assistant Professor at Cincinnati Children's Hospital Medical Center
View his full bio-data here.

b) Thiyam Ramsing Singh did his BS from DM College, Manipur and MS from Manipur University and completed his PhD from Central Drug Research Intistitue, India,
He is a Post Doctoral fellow at Cincinnati Children's Hospital Medical Cente.

Check the link for the abstract of this paper here.


*Information culled from NIH (National Institutes of Health)
This article was webcasted on 23rd August 2005

* Comments posted by users in this discussion thread and other parts of this site are opinions of the individuals posting them (whose user ID is displayed alongside) and not the views of e-pao.net. We strongly recommend that users exercise responsibility, sensitivity and caution over language while writing your opinions which will be seen and read by other users. Please read a complete Guideline on using comments on this website.




LATEST IN E-PAO.NET
  • Inaugural Day Sangai Festival :: Gallery
  • Featured Photo for 2017 #5 :: Gallery
  • Kokkhum Festival #2 :: Gallery
  • Seitinmang, Laljangam, Parihal: eMing
  • Khamba Thoibi & Poems on Manipur : Rvw
  • Significance of learning Chinese language
  • JFA condemns Tripura scribe's murder
  • Zeliang calls for NE Tourist Circuit creation
  • Shillong Lajong I-League Squad 2017/18
  • Tourism Potential of Manipur
  • Sangai Run-Marathon @Sendra #1 :: Gallery
  • On Peace Deal & Framework Agreement #1
  • 22nd Winners' Cup (Football) #1 :: Gallery
  • The charge of sisters :: Poem
  • Reorganisation of North Eastern Council #2
  • DAMMS Freshers / Literary Meet 2017
  • (Blank Editorial)
  • Culturals @Mera Houchongba #2 :: Gallery
  • Kang Chingba @ Wangkhei :: Gallery
  • North East Fashion Week #2 :: Gallery
  • Know The Meetei
  • Indo-Naga Peace Process :: Articles
  • Not just the Gateway
  • Use milk for silky smooth skin
  • Mobile Application for Sangai Festival
  • Manipuri Mega Photo Contest Finalist
  • 5 point resolution on Naga Political Issue
  • NE is least favoured tourist destination
  • Final: Hazari/Tombi Polo #1 :: Gallery
  • Sangai Festival 2017- Events Schedule
  • #TB hotspot cannot be on blindspot
  • United Metal 3.0 @Imphal
  • My name is Kom, Mary Kom
  • Swachch Bharath Swasth Bharath
  • Sangai Festival 2017- Online booking site
  • The Killing Fields (2013-17) :: Timeline
  • Mary set on Olympic gold
  • For every causes, there is a reason
  • Moibung Khunou -near khurkhul :: Gallery
  • Miss Kut #4 :: Gallery
  • On the Naga Framework Agreement
  • Media Challenge: Glance from hills #1
  • GIS day at NIT Manipur
  • Pangal Leader Mohammed Hanif Shah
  • NPF questions Speaker convening meet
  • Painting Exhibition by Babli Das (Tripura)
  • Indo-Naga Talks 2017 :: News Timeline
  • Looking out for possible measures
  • Manipur Sangai Festival 2016 #7 : Ooba
  • Cultural Program @ MCA :: Gallery
  • Ningol ChakKouba @MBC #3 :: Gallery
  • Oh dear Daddy, see I a Native Proud: Poem
  • Buddha's metta and karuna #3
  • Narendra Modi will never play Nehru
  • Photo Caption Contest by Whakal.com
  • General Call to All Former NPF Leaders
  • Penguin Readathon & Book Gifting
  • ENNG opposes inclusion of TCL..
  • Report alarm for Arunachal
  • Loktak witness drastic fall in migratory birds
  • Lecture on 'Rohingya Resettlement'
  • 'Weaves of Ching-tam' @London :: Gallery
  • Opening: Jadonang Football #1 :: Gallery
  • Robert's Weaves of valley & hills at London
  • Remembering boy..felled by fake encounter
  • Sangai Photo Awards 2017 : Contest
  • Meeyam meekup nahum singna leibiyu
  • HighWays : Govt. needs seriousness
  • Singcha Wuya Won @Kamjong #4 :: Gallery
  • SDG Consultation: NE :: Gallery
  • North East Fashion Week #1 :: Gallery
  • Distribution Patterns of the Asian Eye
  • Sustainable Development Goal Consultation
  • Wrangle in Mapithel dam: Legal perspective
  • In the Slums of Heaven :: Poem
  • Wreath Laying Ceremony for AR Martyrs
  • Time to take a bow, Robert
  • Create jobs for NE to stop trafficking
  • March: Mera Houchongba #4:: Gallery
  • Sin-Lang Fest @DM College #2 :: Gallery
  • Sangai Festival: Ideas for a change
  • A shadowy dreamer :: Poem
  • Winter - A blessing in disguise for us ...
  • Course in Nanotechnology at NEHU
  • Pamel : Serene Natural Hub, near Lamlai
  • Vacancy at YVU Financial Services, Thoubal
  • System Operators @PR Enterprise, Khurai
  • Just by showing concern will not change..
  • Food Stall @Phayeng #2 :: Gallery
  • Miss Kut #3 :: Gallery
  • The moment :: Poem
  • Board exams decoded
  • 3rd NE Fashion at Itanagar: Day 2
  • Conference : North East in Globalized Era
  • NE-IAS launched to support Startup India
  • Painting Competition on Conservation
  • Ramkung Pamei is new MHJU Chief
  • Priyogopal (Senior Artist)- Photo :: eRang
  • Kabui Dance @Jadonang Football:: Gallery
  • Fashion @NE Festival, Delhi :: Gallery
  • Deviance and Corruption in Kangleipak
  • Applied health research is vital to #endTB
  • 3rd NE Fashion at Itanagar: Day 1
  • Tri-nation Motorcycle Rally reach Imphal
  • Traffic woes continues
  • Kwatha festival #1 :: Gallery
  • Kokkhum Festival #1 :: Gallery
  • Special Rapporteur on Human Rights
  • The threat to balkanize Manipur
  • Cry of a Dying River - 6 :: Poem
  • Biological based integrated Congress grass
  • 3rd Audition of Fagi Unplugged
  • Sadar Hills District Demand: News Timeline
  • Of clean environment
  • Paonam Lily (Archery) Reception :: Gallery
  • North East Fest @ Delhi :: Gallery
  • Girls Football- Nov 4 #2 :: Gallery
  • IBSD, India & VITO, Belgium signed MOU
  • First angioplasty for in-stent restenosis
  • RIST Popular Talk-33: Quantum Hall states
  • Commonwealth alumni event of NE
  • Lecture on The Rohingya Conundrum
  • Tri-National Motorcycle Rally
  • 3rd North East Fashion Week at Itanagar
  • ILP Nov 30 deadline: Why not only for valley
  • Expected changes, do we see ?
  • Festival of Raas Leela #2 :: Gallery
  • Sin-Lang Fest @DM College #1 :: Gallery
  • Hari Uthan- Kang Chingba #2 :: Gallery
  • Code of silence: Concealing gender justice
  • God Rules Over All :: Poem
  • Five day 'Flower Show' at Ukhrul
  • Go birding to honour Bird Man of India
  • Inner Line Permit (ILP) Demand :: Timeline
  • Uphul Waiphul and Leikhom Leinang
  • A reminder to Central Govt.
  • Ningol Chak-Kouba @Pune :: Gallery
  • Miss Kut #2 :: Gallery
  • Meitei Pictographic Writings :: Book Review
  • Careers related to mental health
  • Beauty & Money for a purpose
  • Human rights infractions in Mapithel Dam
  • AMAND Ningol Chakouba at Pune : Report
  • Chef Required at Kakching
  • NHPC Raising day at Loktak Power Station
  • Of ST demand, ILP, peace talk
  • For elderly people
  • Prof. Nongmaithem Tombi Singh : A Profile
  • Hazari/ Tombi Polo Tournament #2:: Gallery
  • U-17 Footballer honored by Guv :: Gallery
  • Just in favour of nocturnal life
  • Dance of Fire Flies at Autumn :: Poem
  • North East Festival bids farewell
  • Agenda of Govt spelt out at DBC, Maram
  • Nurturing the future
  • Ningol Chak-Kouba @Delhi #2:: Gallery
  • NE Fashion Weekend @Delhi #1 :: Gallery
  • History will not forgive us
  • A girl :: Poem
  • Pre-merger political party struggle
  • JRF wanted at NIT Silchar
  • March: Mera Houchongba #3:: Gallery
  • Girls Football- Nov 4 #1:: Gallery
  • Taxi- raising Air Pollution in Ukhrul
  • Skill development training with MUDA
  • Pui Thangamliu -Photos #1 :: eRang
  • NH7 Weekender [28 October] :: Gallery
  • Surjalal: Fellow of American Physical Society
  • Salesian College Grabs UK Project
  • Prime focus
  • Miss Kut #1 :: Gallery
  • Hari Uthan- Kang Chingba #1 :: Gallery
  • Kangujam Chinglensana (Hockey) feted
  • Chavang Kut @Tengnoupal :: Gallery
  • Sub-Junior Girls Football #2:: Gallery
  • Namsai gets Buddha relic from Thailand
  • Ningol Chak-Kouba @Delhi #1:: Gallery
  • 3rd Ningol Chakouba, Delhi : A Report
  • Dr. Rahejuddin Sheikh : Best Director Award
  • Chothe: Shabu Hong Rein :: Gallery
  • Eyek Tamba :: Learn Manipuri script
  • Candle light for Belinda Morse :: Gallery
  • Exhibition of Pottery Crafts #2 :: Gallery
  • Phayeng Cultural programme :: Gallery
  • Khongjom War Memorial #3 :: 360 ° View
  • Ichangi Laidhi #1 :: eRang
  • Ningol Chakkouba by Paomee:: Gallery
  • Ningol Chakkouba @Kolkata :: Gallery
  • Ningol to her mapam lamdam :: Gallery
  • Manipuri Calendar for 2018 : Download it
  • Mera Men Tongba :: Gallery
  • FIFA U-17 Profile :: Kh Ninthoinganba
  • FIFA U-17 Profile :: Thounaojam Jeakson
  • FIFA U-17 Profile :: Nongdamba Naorem
  • FIFA U-17 Profile :: Dheeraj Moirangthem
  • FIFA U-17 Profile :: Amarjit Kiyam (Captain)
  • FIFA U-17 Profile :: Thangjam Boris
  • FIFA U-17 Profile :: Wangjam Suresh
  • FIFA U-17 Profile :: Md Shahjahan
  • Old Manipuri Movie #1 :: eRang Classic
  • Landscape of Manipur #7: Wallpaper
  • SPONSORED ADS